Study on changes of antral myoelectric activities in patients with bile reflux gastritis

Objective:Our previous study revealed that patients with bile reflux had severe delay of gastric emptying. In this study, we investigated the possible role of antral dysrhythmias in the pathogenesis of the disease. Methods: Antral myoelectric activities were measured in 13 patients with bile reflux gastritis (group R), 10 patients with non-reflux gastritis (group N)and 7 healthy controls (group C) for at least 30min. Freqencies of slow waves more than 5 cpm,or less than 2 cpm,or irregular activities lasting for more than 1 rain were diagnosed as dysrhythmia. Parameters of mean slow wave freqencies (MSWFs,cpm)and dysrhythmias were compared among 3 groups. Results: MSWFs showed no significant difference among 3 groups, while oecurence of dysrhythmias was higher in group R(7/13,53.8％) than group N (3/10,30％) and group C(1/7,14.3％). Further analysis of severity of dysrhythmias displayed that severe disorders of myoelectric activities were seen in group Rand group N,mild in group C. Conclusios: Severe dysrhythmias in antrum may be of significant importance in pathogenesis of bile reflux gastritis.