A clinical analysis on 114 cases of fever of unknown origin

Objective:To investigate the causes and diagnostic methods of fever of unknown irigin(FUO).Methods:The clinical data of 114 patients with FUO were analyzed retrospectively.Results:The definite diagnosis was finally made in 90 cases,the definite diagnostic rate being 78.9%,24 cases(21.1%) failed to be diagnosed.63 definite cases(70.0%) were caused by infectious diseases;15 cases(16.7%) were caused by connective tissue diseases.12 cases(13.3%) were due to tumors and malignant diseases.a final diagnosis was made respectively by serology and(or) bacteriology(45.6%);biopsy(3.3%);bone marrow examination(8.9%);radiology(22.2%);clinical course and treatment(20.0%).Conclusion:Most patients with FUO could be diagnosed according to the clinical course and necessary aided examination.Infectious diseases,connective tissue diseases and tumor diseases were the main causes of FUO in the studied group.