2013•National Medical Frontiers of ChinaRequires access

Fungal genital tract inflammation etiology and main pathogenic bacteria of the minimum inhibition concentration detection

Wenchao Yu

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Abstract

Objective To identify the main pathogenic bacteria and to detect the 9 antifungal drugs' MIC of Candida albicans,which isolated from Vulvovaginal Candidiasis and Candidal Balanoposthitis.Methods The Candida spp.were cultured and identified conventionally.The medical susceptibility test was performed by MIC methods to Candida albicans.Results Among 53 strains of Candida,the most common organisms were Candida albicans(84.91%),then was biovar Candida albicans(3.77%),Candida glabrata(3.77%),Candida parapsilosis(3.77%),Candida guilliermondii(1.87%),Candida tropicalis(1.87%).Drug resistance rate from high to low was Fluconazol,Itraconazole,Miconazole,Ketoconazole,Econazole,Clotrimazole,Flucytosine,Amphotericin and Mycostatin,respectively,and the drug resistance rate was greater than fifty percent in 6 drugs of total.Conclusions Candida albicans was the most commonly cause of Vulvovaginal Candidiasis or Candidal Balanoposthitis and multi drug resistance is generalized.It is important to use the antifungal drug according the result of drug sensitive test.

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Objective To identify the main pathogenic bacteria and to detect the 9 antifungal drugs' MIC of Candida albicans,which isolated from Vulvovaginal Candidiasis and Candidal Balanoposthitis.Methods The Candida spp.were cultured and identified conventionally.The medical susceptibility test was performed by MIC methods to Candida albicans.Results Among 53 strains of Candida,the most common organisms were Candida albicans(84.91%),then was biovar Candida albicans(3.77%),Candida glabrata(3.77%),Candida parapsilosis(3.77%),Candida guilliermondii(1.87%),Candida tropicalis(1.87%).Drug resistance rate from high to low was Fluconazol,Itraconazole,Miconazole,Ketoconazole,Econazole,Clotrimazole,Flucytosine,Amphotericin and Mycostatin,respectively,and the drug resistance rate was greater than fifty percent in 6 drugs of total.Conclusions Candida albicans was the most commonly cause of Vulvovaginal Candidiasis or Candidal Balanoposthitis and multi drug resistance is generalized.It is important to use the antifungal drug according the result of drug sensitive test.

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Available abstract

Objective To identify the main pathogenic bacteria and to detect the 9 antifungal drugs' MIC of Candida albicans,which isolated from Vulvovaginal Candidiasis and Candidal Balanoposthitis.Methods The Candida spp.were cultured and identified conventionally.The medical susceptibility test was performed by MIC methods to Candida albicans.Results Among 53 strains of Candida,the most common organisms were Candida albicans(84.91%),then was biovar Candida albicans(3.77%),Candida glabrata(3.77%),Candida parapsilosis(3.77%),Candida guilliermondii(1.87%),Candida tropicalis(1.87%).Drug resistance rate from high to low was Fluconazol,Itraconazole,Miconazole,Ketoconazole,Econazole,Clotrimazole,Flucytosine,Amphotericin and Mycostatin,respectively,and the drug resistance rate was greater than fifty percent in 6 drugs of total.Conclusions Candida albicans was the most commonly cause of Vulvovaginal Candidiasis or Candidal Balanoposthitis and multi drug resistance is generalized.It is important to use the antifungal drug according the result of drug sensitive test.

Key concepts: Miconazole, Ketoconazole, Candida albicans, Clotrimazole, Microbiology, Candida glabrata, Candida parapsilosis, Econazole

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