Clinical significance and comparison of CRP,WBC and N% in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease

Objective To study the clinical significance of C-reaction protein(CRP),IL-10、white blood cell(WBC) counter and neutrophilgranulocyte ratio(N% ) in acute exacerbations of hospitalized patients with chronic obstructive pulmonary disease(COPD) .Methods The serum CRP levels,IL-10、the gross of WBC and N% were detected of the same 30 inpatients with acute exacerbations of COPD before treatment and after getting better.The masculine rates during acute exacerbations and the negative rates after getting better of abovementioned indexes were observed.Results ①The levers of CRP、IL-10、WBC and N% of patients after getting better were significantly lower than those before treatment(P 0.01) .② The masculine rates of CRP、IL-10 and N% were higherthan that of WBC during acute exacerbations,and there were statistics differences between them(P 0.01) .③The negative rates ofCRP、IL-10 and WBC were higher than that of N% after getting better,and there were statistics differences between them(P 0.01) .Conclusion The serum CRP level is a sensitive index in COPD patients with acute exacerbations,and it is also a good index to judge the early therapeutic efficacy in COPD patients with acute exacerbations.