2015•Acta Medicinae SinicaRequires access

Clinical analysis of proton magnetic resonance spectroscopy for traumatic craniocerebral injury

LI Zai-y

Abstract

Objective:To investigate the clinical significance of proton magnetic resonance spectroscopy OH-MRS) on extent and prognosis of moderate traumatic craniocerebral injury(TCI).Methods:30 moderate TCI patients and 10 volunteers were accepted proton magnetic resonance spectroscopy.The change of N-acetyl aspartate(NAA),choline(Cho),creatineCCr),lactate(Lac),NAA/Cho,NAA/Cr and Cho/Cr of ipsilateral and contralateral white matter of brain were observed.Results:The value of NAA/Cho and NAA/Cr in white matter of patients was decreased significantly than that of control group,however the value of Cho/Cr was significantly increased.The value changes of NAA/Cho,NAA/Cr,Cho/Cr in white matter of patients was correlated with GCS and GOS.Conclusion;Proton magnetic resonance spectroscopy has an important guiding significance for the early diagnosis and treatment of moderate traumatic craniocerebral injury.

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Key concepts: Proton magnetic resonance, Magnetic resonance imaging, White matter, Choline, Traumatic brain injury, Nuclear magnetic resonance spectroscopy, Medicine, Spectroscopy