Hydrogenation of m- Mononitrophenyl-β-hydroxyethyl Sulfone to m-Aminophenyl-β-hydroxyethyl Sulfone

This report is related to a process for reduction of m mononitrophenyl β hydroxyethyl sulfone to produce m aminophenyl β hydroxyethyl sulfone.We made a thorough study on the technolgical conditions.The hydrogenation process is performed at a temperature of 70℃,a pressure of 3.5MPa,and a stirring speed of 800 r/min.The catalyst contains w =0.05 by weight of Pd/C based on the raw material.The reaction medium used in the reaction is alcohol,and alcohol∶material=1∶1( m∶m) at pH=7~8.Under the optimum conditions,the yield of m aminophenyl β hydroxyethl sulfone is 99.7%.After the catalyst used 5 times,the yield of reaction is 81.5% with refined materials.