Changes of erythrocytic immune function and T lymphocyte subsets of peripheral blood in patients with lung cancer and then clinical significance

Objective:To study the changes of erythrocytic immune function and T lymphocyte subsets in lung cancer patients.Methods:Erythrocyte immune functions and T lymphocyte subsets were detected in 55 cases of lung cancer;15 cases of lung benign neoplasm and 20 healthy persons were chosen as control.Results:(1)RRC-C3bRR,CD3 +,CD4 +,CD8 +,CD4 +/CD8 + ratio of lung cancer patients were significantly lower than those of healthy group( P 0 05);however RBC-1CR of lung cancer patients were significantly higher than those of lung benign neoplasm and healthy group( P 0 05) in turn.(2)RBC-C3bRR,CD3 +,CD4 +,CD4 +/CD8 + ratio of Ⅲa,Ⅲb staged lung cancer patients were significantly lower than those of Ⅰ,Ⅱ stages and healthy group ( P 0 05);RBC-1CR of Ⅲa,Ⅲb stage in lung cancer patients was significantly higher than those of healthy group( P 0 01),CD3 +,CD4 +,CD8 + of stage Ⅰ,Ⅱ patients were significantly lower than those of healthy group( P 0 01),and RBC-1CR of stage Ⅰ,Ⅱ patlents was significantly higher( P 0 01).Conclusion:Detection of erythrocyte immune functions and T lymphocyte subsets may be useful in the diagnosis,treatment and prognos is of lung cancer.