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2011•Zhongguo yiyuan ganranxue zazhiRequires access

Study on peripheral blood T lymphocyte subsets of patients with lung cancer and lung infection

Qiong Tang

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Abstract

OBJECTIVE To study the variation of peripheral blood T lymphocyte subsets of patients with lung cancer and lung infection.METHODS A total of 93 patients with lung cancer in our hospital from Jan 2008 to Dec 2010 were selected as research object,and they were divided into control group(without infection group)47 cases and observation group(with infection group)46 cases,then the CD3+,CD4+,CD8+,CD4+/CD8+ and NK of two groups were analyzed and compared.RESULTS The CD3+,CD4+,CD4+/CD8+ and NK of observation group [(60.82±5.96)%,(30.58±3.78)%,1.02±0.15,(19.20±5.97)%] were lower than those of control group [(65.38±5.89)%,(37.85±3.69)%,1.43±0.18,(22.76±6.12)%].CD8+ was higher than that of control group [(25.76±2.58)% vs(29.75±2.66)%],(P0.05).And CD3+,CD4+,CD8+,CD4+/CD8+ and NK of different stages all showed this regulation.CONCLUSION The patients with lung cancer and lung infection are more immunocompromised,and it should pay attention to the course of treatment.

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OBJECTIVE To study the variation of peripheral blood T lymphocyte subsets of patients with lung cancer and lung infection.METHODS A total of 93 patients with lung cancer in our hospital from Jan 2008 to Dec 2010 were selected as research object,and they were divided into control group(without infection group)47 cases and observation group(with infection group)46 cases,then the CD3+,CD4+,CD8+,CD4+/CD8+ and NK of two groups were analyzed and compared.RESULTS The CD3+,CD4+,CD4+/CD8+ and NK of observation group [(60.82±5.96)%,(30.58±3.78)%,1.02±0.15,(19.20±5.97)%] were lower than those of control group [(65.38±5.89)%,(37.85±3.69)%,1.43±0.18,(22.76±6.12)%].CD8+ was higher than that of control group [(25.76±2.58)% vs(29.75±2.66)%],(P0.05).And CD3+,CD4+,CD8+,CD4+/CD8+ and NK of different stages all showed this regulation.CONCLUSION The patients with lung cancer and lung infection are more immunocompromised,and it should pay attention to the course of treatment.

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Available abstract

OBJECTIVE To study the variation of peripheral blood T lymphocyte subsets of patients with lung cancer and lung infection.METHODS A total of 93 patients with lung cancer in our hospital from Jan 2008 to Dec 2010 were selected as research object,and they were divided into control group(without infection group)47 cases and observation group(with infection group)46 cases,then the CD3+,CD4+,CD8+,CD4+/CD8+ and NK of two groups were analyzed and compared.RESULTS The CD3+,CD4+,CD4+/CD8+ and NK of observation group [(60.82±5.96)%,(30.58±3.78)%,1.02±0.15,(19.20±5.97)%] were lower than those of control group [(65.38±5.89)%,(37.85±3.69)%,1.43±0.18,(22.76±6.12)%].CD8+ was higher than that of control group [(25.76±2.58)% vs(29.75±2.66)%],(P0.05).And CD3+,CD4+,CD8+,CD4+/CD8+ and NK of different stages all showed this regulation.CONCLUSION The patients with lung cancer and lung infection are more immunocompromised,and it should pay attention to the course of treatment.

Key concepts: Lung cancer, CD8, Lung, Peripheral blood, CD3, Medicine, Internal medicine, Gastroenterology

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