The New Progress of Micafungin Research
Guan Ya-peng
Abstract
Guan Ya-peng
Abstract
Micafungin is a new echimocandin which represents antifungal drug class and exhibits broad-spectrum activity.Micafungin acts by inhibiting the production of 1,3-β-D-glucan which is a key component in fungal cell wall synthesis and has selective toxicity to fungi.This paper reviewed the in vitro antifungal activity,pharmacokinetics and drug interactions of micafungin.
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Micafungin is a new echimocandin which represents antifungal drug class and exhibits broad-spectrum activity.Micafungin acts by inhibiting the production of 1,3-β-D-glucan which is a key component in fungal cell wall synthesis and has selective toxicity to fungi.This paper reviewed the in vitro antifungal activity,pharmacokinetics and drug interactions of micafungin.
Key concepts: Micafungin, Antifungal, Echinocandins, Antifungal drug, Chemistry, Pharmacokinetics, Prodrug, Broad spectrum