2010Hainan Yixueyuan xuebaoRequires access

Efficacy comparison of cervical cancer screening system and liquid based cytology test in detection of cervical lesions

Weihong Li, Jin Ho Song, Zhang JunXiao, Xiaomei Wu, Hua Chen, Zeng RongRong, Wang Li

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Abstract

Objective:To study the value of cervical cancer screening system and liquid based cytology test in detection of cervical lesions.Methods:Cervical cancer screening system,liquid based cytology test and pathological test were performed in a 1 201 cases,and the results of the former two were compared with pathological outcomes.Results:A total of 316,207 and 115 cases were shown as positive according to cervical cancer screening system,liquid based cytology test and pathological test respectively indicating sensitivity of 81.7%,71.3%;specificity of 79.6%,88.5%;false negative rate of 18.3%,28.7%;and false positive rate of 20.4%,11.5% for cervical cancer screening system and liquid based cytology test.Sensitivity of cervical cancer screening system was slightly higher than that of the liquid based cytology test,while the difference was insignificant(P0.05).Conclusions:Efficacy of cervical cancer screening system is better than that of liquid based cytology test.With low false negative rate and comparatively low false positive rate,it might be used alone as primary screening method for cervical lesions in China.

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What this paper is about

Objective:To study the value of cervical cancer screening system and liquid based cytology test in detection of cervical lesions.Methods:Cervical cancer screening system,liquid based cytology test and pathological test were performed in a 1 201 cases,and the results of the former two were compared with pathological outcomes.Results:A total of 316,207 and 115 cases were shown as positive according to cervical cancer screening system,liquid based cytology test and pathological test respectively indicating sensitivity of 81.7%,71.3%;specificity of 79.6%,88.5%;false negative rate of 18.3%,28.7%;and false positive rate of 20.4%,11.5% for cervical cancer screening system and liquid based cytology test.Sensitivity of cervical cancer screening system was slightly higher than that of the liquid based cytology test,while the difference was insignificant(P0.05).Conclusions:Efficacy of cervical cancer screening system is better than that of liquid based cytology test.With low false negative rate and comparatively low false positive rate,it might be used alone as primary screening method for cervical lesions in China.

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Available abstract

Objective:To study the value of cervical cancer screening system and liquid based cytology test in detection of cervical lesions.Methods:Cervical cancer screening system,liquid based cytology test and pathological test were performed in a 1 201 cases,and the results of the former two were compared with pathological outcomes.Results:A total of 316,207 and 115 cases were shown as positive according to cervical cancer screening system,liquid based cytology test and pathological test respectively indicating sensitivity of 81.7%,71.3%;specificity of 79.6%,88.5%;false negative rate of 18.3%,28.7%;and false positive rate of 20.4%,11.5% for cervical cancer screening system and liquid based cytology test.Sensitivity of cervical cancer screening system was slightly higher than that of the liquid based cytology test,while the difference was insignificant(P0.05).Conclusions:Efficacy of cervical cancer screening system is better than that of liquid based cytology test.With low false negative rate and comparatively low false positive rate,it might be used alone as primary screening method for cervical lesions in China.

Key concepts: Medicine, Cervical cancer, Cytology, Liquid-based cytology, Pathological, Cervical cancer screening, Pap test, False positive rate

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