Relations of basic blood glucose level distribution and prognosis in critical diseases

Objective To observe the distribution features of blood glucose level(BGL) and analyze the relationship between BGL and critical degree,prognosis in critical ills.Methods There were 207 critical patients who were tested early blood glucose in admitted 2 hours.According to tested BGL of earlier stress period,they were divided into three groups: Group A,BGL4.5mmol/L;Group B,BGL 4.5-8.3mmol/L;Group C,BGL8.3mmol/L.Assessed their scores of APPCHEⅡ,GCS,MODS,SOFA and condition of infection,vasoactive drug utilization and prognosis.Analysed relationship bewteen early BGL and these parameter.Results The patients' blood glucose range was 0.58-22.08mmol/L and mean BGL was 7.39±3.05mmol/L;The APACHEⅡscore(10.30±6.23) and the blood lactic acid value(1.46±0.99mmol/L) of Group B were significantly less than Group A(22.54±13.46;5.07±2.98mmol/L) and Group C(14.74±8.49;2.82±1.74mmol/L)(P0.05).The incidence rates of MODS,infection,vasoactive drug utilization and 28th day survival rate in Group A were 75%,62.5%,50% and 54.2%,respectively.And they were significantly different to Group B and C(P0.01);BGL in Group A was connected with scores of APACHE Ⅱ,GCS,MODS,SOFA and dopamine dosage,and BGL in Group C was only connected with score of APACHE Ⅱand GCS(P0.01).Conclusion The main distribution of basic blood glucose level in critical patients during early period are in 4.5-8.3 mmol/L which has better prognosis and safety,and it may be considered to reasonable blood glucose level.When the blood glucose level 4.5 mmol/L,it can reveal severe degree of critcal ill and worse prognosis.