Clinical study of epidural and general anesthesia under BIS monitoring in the thoracic surgery

Objective:To evaluate the effects and safety of epiduarl anesthesia combined with general anesthesia under bispectarl index monitoring. Methods:40 patients scheduled for thoracic surgery were randomly divided into general anaesthesia group (group GA,n=20) and epiduarl anesthesia combined with general anesthesia group (group GEA,n=20),and bispectarl index was maintained between 50 and 55 during anaesthesia. BIS,MAP,HR were recorded before anesthesia (T0),before tracheal intubation (T1),1 minute after tracheal intubation (T2),at the time of skin incision (T3),costal bone removal (T4) and extubation (T5) respectively. The quantities of anesthetic and palinesthesia time were assessed. Results:MAP and HR reduced significantly in two groups before tracheal intubation than before anesthesia (P0.05),1 minute after tracheal intubation and at the time of extubation,MAP and HR in group GA increased (P0.05),and those in group GEA have no significant changes (P0.05). Palinesthesia time was shorter and the quantities of anesthetic was less in group GEA than those in group GA (P0.05). No case of awareness during anesthesia happened in two groups. Conclusion:Epiduarl anesthesia combined with general anesthesia under bispectarl index monitoring can avoid awareness during anesthesia,reduce the cardiovascular effects of tracheal intubation and extubation,lessen anesthetic and shorten palinesthesia time.