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Synthesis of 4-(2-dimethylamino)-ethoxy benzylamine

Shuangxi Liu

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Abstract

Objective To synthesize 4-(2-dimethylamino)-ethoxy benzylamine in order to reduce the cost of production.Methods 4-(2-dimethylamino)-ethoxy benzylamine was synthesized with N,N-dimethylethanolamine as starting material,and then chloridation,etherification,oximation and hydrogenation were adopted.Results The target compound was obtained and the structure was confirmed by 1H-NMR.Conclusion The total yield was 65.6% and this method had mild reaction conditions,cheap raw materials and it was suitable for industrial production.

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Objective To synthesize 4-(2-dimethylamino)-ethoxy benzylamine in order to reduce the cost of production.Methods 4-(2-dimethylamino)-ethoxy benzylamine was synthesized with N,N-dimethylethanolamine as starting material,and then chloridation,etherification,oximation and hydrogenation were adopted.Results The target compound was obtained and the structure was confirmed by 1H-NMR.Conclusion The total yield was 65.6% and this method had mild reaction conditions,cheap raw materials and it was suitable for industrial production.

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Available abstract

Objective To synthesize 4-(2-dimethylamino)-ethoxy benzylamine in order to reduce the cost of production.Methods 4-(2-dimethylamino)-ethoxy benzylamine was synthesized with N,N-dimethylethanolamine as starting material,and then chloridation,etherification,oximation and hydrogenation were adopted.Results The target compound was obtained and the structure was confirmed by 1H-NMR.Conclusion The total yield was 65.6% and this method had mild reaction conditions,cheap raw materials and it was suitable for industrial production.

Key concepts: Benzylamine, Alkoxy group, Yield (engineering), Raw material, Chemistry, Production cost, Organic chemistry, Catalytic hydrogenation

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