Clinical study of treatment of severe subarachnoid hemorrhage with closed lumbar pool circulation drainage replacement of cerebrospinal fluid

Objective To investigate the clinical value of closed lumbar pool circulation drainage replacement(CLPCDR) of cerebrospinal fluid(CSF) for severe subarachnoid hemorrhage(SAH).Methods Two hundred ninety-eight patients with severe SAH were randomly divided into two groups,i.e.treatment group(n=146,treated with CLPCDR of CSF) and control group(n=152,treated with intermittent replacement of CSF).The curative effects were compared between both the groups.Results National Institute of Health stroke scale(NIHSS),Barthel activity of daily living index and GCS in the treatment group were(6.34±5.15),(91.39±15.32) and(13.98± 1.04) points respectively,and they in the control group were(15.91±7.26),(53.86±13.39) and(10.05±1.46) points respectively.There were significant differences in them between both the groups(P0.01).The incidence of the complications,including cerebral vasospasm in 15 cases,hydrocephalus in 28 cases,intracranial rebleeding in 8 cases and intracranial infection in 1 case,was 35.62%(52/146),and the death rate was 13.01%(19/46) in the treatment group.The incidence of the complications,including cerebral vasospasm in 24 cases,hydrocephalus in 45 cases,intracranial rebleeding in 13 cases and intracranial infection in 3 cases was 55.92%(85/152),and the death rate was 25.66%(39/152) in the control group.The durations of headache,time from hemorrhage to clearing up SAH and length of hospital stay were(6±2.63),(4±1.7) and(23±3.1) days in the treatment group,and(15±1.72),(11±2.6) and(39±3.7) days respectively in the control group.There were significant differences in them between both the groups(P 0.05).Conclusion The CLPCDR of CSF is a simple,safe and effective method to treat severe SAH.