CT Diagnosis of Intrahepatic Peripheral Cholangiocarcinoma

Objective To investigate CT features and anatomy characters of intrahepatic peripheral cholangiocarcinoma,and differential diagnosis of intrahepatic space-occupying lesions. Methods CT findings of 35 cases of intrahepatic peripheral cholangiocarcinoma surgically and pathologically confirmed were retrospectively analyzed. Results Of all 35 cases,tumor involved left lobe of liver(24 cases),right lobe(9 cases),both left and right lobes(2 cases).28 cases were single mass with a diameter of 3~10 cm and 7 cases were multiple lesions with various sizes.Dilation of intrahepatic biliary duct(26 cases),hepatolith(20 cases),atrophy of liver lobe(12 cases),retraction of liver capsule adjacent to the tumor(7 cases) were found.Mild enhancement of the lesion margin in arterial phase and portal-venous phase and linear or reticular enhancement was seen in all cases.In delayed scan there was progress enhancement from periphery to center,at last the lesion was higher than that of normal liver. Conclusions CT features of intrahepatic peripheral cholangiocarcinoma have some extent common characteristics,which are useful in the differential diagnosis of space-occupying lesions in liver,MSCT multi-phase scan is especially useful.