Study on Anti- tumor Activity of Cortinarius Rufo- olivaceus Extract

Taking Cortinarius rufo- olivaceus as materials,the inhibitory effect of petroleum ether,ethyl acetate,n- butanol extract and water extract on 231 breast cancer cells was studied. Obtained the organic phase by ethanol extraction and organic solvent extraction steps,anti- tumor activity of each phase of extracts extracted by MTT method was screened. The result showed that Cortinarius rufo- olivaceus petroleum ether,ethyl acetate and n- butanol extracts on231 breast cancer cells had inhibitory effect,the petroleum ether extract had the best effect,inhibition rate was up to96. 99% when the concentration was 0. 225 mg / m L,but the water extract had weaker inhibition of cancer cell.