The multiple trauma patients and their relation to systemic inflammatory respons and multiple organ dysfunction syndrome

Objective: To investigate multiple trauma patients' relation to systemic inflammatory respons syndrome and multiple organ dysfunction syndrome.Methods: 96 multiple trauma patients were divided into two groups as followed:non-SIRS group,SIRS group(including unsepsis group,sepsis systemic infection group,septic shock group). Calculate each patient's APACHE Ⅱ score and the incidence rates and fatalits of groups.Results: The fatalits and MODS incidence rates of sepsis systemic infection SIRS group and septic shock SIRS group were higher than that of the unsepsis SIRS group. The difference was significant(P 0.05). The incidence rate of SIRS group was higher than that of the non-SIRS group,the difference was significant(P 0.01). The fatalits was higer than 50% if the MODS happened. The higher the APACHE Ⅱ scores were, the higher fatalits would be. The highest fatalies lies in the multiple trauma patients with the severe brain injury.Conclusion: From multiple trauma to SIRS and MODS is one of the clinical common processes advanced gradually. To discover SIRS and adjust inflammatory secondary effectively and prevent the evelopments in early stage is probably the key of reducing the MODS incidence rates and improving the prognosis of the multiple trauma patients especially the severe ones.