Effect of blood pressure control on cardiovascular events in elderly male hypertensive patients

Objective To study the optimal blood pressure of elderly male hypertensive patients by observing whether there is aJ-shaped curveduring antihypertensive treatment.Methods Eight hundred and forty-six elderly male hypertensive patients were divided into≤120 mm Hg(SI group,n = 213),121—130 mm Hg(S2 group,n = 215 ),131 -140 mm Hg(S3 group,n = 219), 141—150 mm Hg(S4 group,n= 121),150 mm Hg(S5 group,n = 78)according to their SBP, and into 60 mm Hg(D1 group,n= 107),61—70 mm Hg(D2 group,n = 258),71—80 mm Hg (D3 group,n = 339),81—90 mm Hg(D4 group,w = 125),and 90 mm Hg(D5 group,n=17) according to their DBP.Relation of blood pressure control with cardiovascular events was analyzed. Results The incidence of death due to cardiovascular events,fatal cerebral stroke,nonfatal myocardial infarction(MI) and cerebral stroke was the highest in S5 group while the incidence of death due to cardiovascular events,CHD,fatal cerebral stroke and nonfatal MI was the lowest in S4 group(P0.05,P0.01).The incidence of death due to all causes,cardiovascular events, CHD,fatal cerebral stroke,nonfatal MI and cerebral stroke was the highest in D5 group while the incidence of death due to all causes,cardiovascular events and CHD was the lowest in D4 group (P0.05).Conclusion J-shaped curve can be observed in elderly male hypertensive patients during antihypertensive treatment.Their optimal blood pressure is 140—150/80—90 mm Hg.