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Effect of Bushenyizhi Decoction on the Inhibition Mechanism of Apoptosis of Cultured Hippocampal Neuron

Tcm Guangzhou

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Abstract

OBJECTIVE: To explore the effect of complex prescription of natural nootropic drugs, Bushenyizhi decoction, on the inhibition mechanism of apoptosis of cultured hippocampal neuron. METHOD: Hippocampal neurons were cultured with the serum of the treated and the controls; and fluorescent labeling and statistics analysis were carried on. RESULTS: Apoptosis rate of the serum of treated was significant lower than that of the model and the Hup A, and higher than that of the young, CONCLUSION: The serum of the treated can inhibit the apoptosis of culture hippocampal neurons.

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What this paper is about

OBJECTIVE: To explore the effect of complex prescription of natural nootropic drugs, Bushenyizhi decoction, on the inhibition mechanism of apoptosis of cultured hippocampal neuron. METHOD: Hippocampal neurons were cultured with the serum of the treated and the controls; and fluorescent labeling and statistics analysis were carried on. RESULTS: Apoptosis rate of the serum of treated was significant lower than that of the model and the Hup A, and higher than that of the young, CONCLUSION: The serum of the treated can inhibit the apoptosis of culture hippocampal neurons.

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Available abstract

OBJECTIVE: To explore the effect of complex prescription of natural nootropic drugs, Bushenyizhi decoction, on the inhibition mechanism of apoptosis of cultured hippocampal neuron. METHOD: Hippocampal neurons were cultured with the serum of the treated and the controls; and fluorescent labeling and statistics analysis were carried on. RESULTS: Apoptosis rate of the serum of treated was significant lower than that of the model and the Hup A, and higher than that of the young, CONCLUSION: The serum of the treated can inhibit the apoptosis of culture hippocampal neurons.

Key concepts: Decoction, Hippocampal formation, Apoptosis, Neuron, Mechanism (biology), Nootropic, Pharmacology, Chemistry

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