Analysis of the influence of different periods of mannitol treatment for the secondary brain edema on the patients with spontaneous intracerebral hemorrhage

Objective: To probe whether the secondary brain edema would get heavy on the patients of spontaneous intracerebral hemorrhage(SICH),when the periods of mannitol were longer(more than 3 days and less than 7 days).Methods: Eight-two patients of SICH(volume more than 3 mL) were reviewed with CT scan within 24 h and 4-7 day after SICH onset.Based on the period of mannitol treatment is more than 3 days or not,the patients were divided into two groups compared the volume of secondary brain edema.Results: To compare the volume of secondary brain edema between the group of mannitol treatment period less than 3 days [(21.7±12.7)mL] and the group of mannitol treatment period more than 3 days [(27.7±17.8)mL],there is no statistical differences between two groups of the volume of secondary brain edema.Conclusion: A longer period(less than 7 days) of mannitol treatment wouldn't enlarge second-ary brain edema on patients with SICH.