2002•Unpublished venueRequires access

Study on the Pharmacokinetics of Qianlietai Tablets after Oral Adminstration in Rabbits

DI Duo

Abstract

An analytical method for the determination of stachydrine concentration in rabbits after oral administration with 4 % suspension of tablet powder was established. The pharmacokinetics in rabbits is a two compartment model. The main pharmacokinetic parameters are: C\- max is 6.29±0.84 μg/mL, T\- max is 3.36±0.64 h; T\- 1/2\+α is 5.35±3.79 h; T\- 1/2\+β is 32.38±24.33 h; AUC is 208.15±118.4 μg/(mL·h)

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Key concepts: Pharmacokinetics, Oral administration, Pharmacology, Chemistry, Chromatography, Medicine