Multiple factors of atrial fibrillation in patients with chronic heart failure

Objective To explore multiple factors of atrial fibrillation in patients with chronic heart failure through retrospective analysis of clinical data.Methods Three hundred and thirty patients with chronic heart failure(NYHAII-IV) treated in the Hospital of Langxi County during the period from January 2009 to January 2011 were assigned into AF group and non AF group according to whether the patients had atrial fibrillation(AF) or not,and the clinical data of the two groups were used for statistical analysis.Results Of 330 patients with chronic heart failure 85 cases(25.76%) with atrial fibrillation were assigned into AF group,while the other 245 patients without atrial fibrillation were in non AF group.Single factor COX regression analysis showed that severe heart failure(III + IV level),age,diabetes,left ventricular hypertrophy,left atrialdiameter,blood urea nitrogen,blood creatinine,blood uric acid and spironolactone were risk factors for atrial fibrillation while ACEI,digitalis,blood sodium and blood chlorine were protective factors for atrial fibrillation.Multivariate COX analysis showed that ACEI was the independent protective factor for primary AF,while severe heart failure and left atrialdiameter of left ventricular hypertrophy were risk factors for AF.Conclusions Severe heart failure and left atrial diameter of left ventricular hypertrophy are risk factors for AF.ACEI is an independent protective factor for primary AF in heart failure patients,which can reduce the incidence of AF.