The Relative Pathogenesis of Chronic Heart Failure Combined with Atrial Fibrillation

Objective: Chronic Heart Failure(CHF) is a common disease of cardiovascular system which threatens to the cycle and quality of life. This research aims to investigate the clinical features of chronic heart failure with atrial fibrillation and to analyze the pathogenesis of chronic heart failure complicated with atrial fibrillation so as to provide a basis for clinical treatment. Methods: 80 cases with chronic heart failure were selected and divided into two groups according to the proportion of 1:1. The patients with normal rhythm were chosen to be the sinus rhythm group, while others with atrial fibrillation were selected to be the atrial fibrillation group. Then the possible factors of atrial fibrillation were compared and analyzed. Results: The LVEF was(0.42±0.08); the E/A was(0.65±0.22); the LAD was(53.4±8.2) mm of the atrial fibrillation group. The LVEF was(0.45±0.09); the E/A was(0.72±0.17); the LAD was(46.7± 7.9) mm of the sinus rhythm group. The heart function indexes of the atrial fibrillation group were lower than those of the patients in sinus rhythm group, while the LAD was significantly higher than that of the sinus rhythm group with statistically significant differences(P0.05). The aldosterone, AngII, BNP, HS and CRP in atrial fibrillation group were higher than those of the patients in the sinus rhythm group with statistically significant differences(P0.05). Conclusion: The pathogenesis of chronic heart failure complicated with atrial fibrillation is related to the neuroendocrine fluid system level and cardiac structure and function, but the specific mechanism needs further study.