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Study on extraction technology for Tongtong Granules by orthogonal design

LI Hong-jian

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Abstract

OBJECTIVE To establish the optimal extraction technology for Tongtong granules.METHODS The orthogonal test was employed for selecting the optimum of extraction technology.The investigation factors were the concentration and volume of alcohol,the time and times of extraction.The evaluation maker were content of puerarin,total Ginkgo flavone glycosides and extraction rate.The contents of active ingredient were detected by HPLC.RESULTS The best extraction condition was as follow:8 times of 70% alcohol,extracted for 2 times,each time for 1h.CONCLUSION The above mentioned extraction technology was feasible,stable,reasonable and replicable,which can provide reference for industrial production.

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OBJECTIVE To establish the optimal extraction technology for Tongtong granules.METHODS The orthogonal test was employed for selecting the optimum of extraction technology.The investigation factors were the concentration and volume of alcohol,the time and times of extraction.The evaluation maker were content of puerarin,total Ginkgo flavone glycosides and extraction rate.The contents of active ingredient were detected by HPLC.RESULTS The best extraction condition was as follow:8 times of 70% alcohol,extracted for 2 times,each time for 1h.CONCLUSION The above mentioned extraction technology was feasible,stable,reasonable and replicable,which can provide reference for industrial production.

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Available abstract

OBJECTIVE To establish the optimal extraction technology for Tongtong granules.METHODS The orthogonal test was employed for selecting the optimum of extraction technology.The investigation factors were the concentration and volume of alcohol,the time and times of extraction.The evaluation maker were content of puerarin,total Ginkgo flavone glycosides and extraction rate.The contents of active ingredient were detected by HPLC.RESULTS The best extraction condition was as follow:8 times of 70% alcohol,extracted for 2 times,each time for 1h.CONCLUSION The above mentioned extraction technology was feasible,stable,reasonable and replicable,which can provide reference for industrial production.

Key concepts: Extraction (chemistry), Chromatography, Puerarin, Ingredient, High-performance liquid chromatography, Active ingredient, Chemistry, Computer science

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