Drug resistance analysis on 194 strains of Pseudomonas aeruginosa

Objective To study the drug resistance of Pseudomonas aeruginosa so as to provide references for rational use of antibiotics in clinic.Methods The clinical distribution and the susceptibility test results of Pseudomonas aeruginosa isolated from our hospital from February,2009 to January,2010 were analyzed retrospectively.Results Among 194 clinical isolates of Pseudomonas aeruginosa,the isolation rate from sputum was highest (90.7%).The isolates mainly caused respiratory tract infections in the patients of neurosurgery (36.5%),neurology (26.3%) and respiration (20.6%) departments.They were highly resistant to gentamicin (74.7%),meropenem (2.1%),cefoperazone/sulbactam(6.2%).Conclusion The resistant rates of Pseudomonas aeruginosa to carbapenems and β-lactam/β-lactamase inhibitors in our hospital are low,which can be selected as the first choice in the empirical treatment of Pseudomonas aeruginosa infections.