ScholarLens Back to search
2010•Parenteral & Enteral NutritionRequires access

The influence of Blackcurrant Polysaccharides on the immune function in mice of hypoimmunity

Xudong Ma

Open publisher page 0 citations

Abstract

Objective:To study influence of Blackcurrant Polysaccharides on the immune function in mice of hypoimmunity.Methods:Immune suppression was induced by cyclophosphamide in mice.Then the mice were treated with oral Blackcurrant Polysaccharides at 0.4,0.8,1.6 g/kg daily for 10 days.The phagocytosis ability of macrophage,IL-2 and the HC50 were observed.Results:There were statistical differences in the thymus index,the spleen index,IL-2 and the HC50 among the high,middle and low dose groups.And there was statistical difference in the phagocytosis ability of macrophage in the high and middle dose groups.The content of hemolytic OD was statistically different between the high dose group and the control group.Conclusion:Blackcurrant Polysaccharides have immune function.

About this research paper

What this paper is about

Objective:To study influence of Blackcurrant Polysaccharides on the immune function in mice of hypoimmunity.Methods:Immune suppression was induced by cyclophosphamide in mice.Then the mice were treated with oral Blackcurrant Polysaccharides at 0.4,0.8,1.6 g/kg daily for 10 days.The phagocytosis ability of macrophage,IL-2 and the HC50 were observed.Results:There were statistical differences in the thymus index,the spleen index,IL-2 and the HC50 among the high,middle and low dose groups.And there was statistical difference in the phagocytosis ability of macrophage in the high and middle dose groups.The content of hemolytic OD was statistically different between the high dose group and the control group.Conclusion:Blackcurrant Polysaccharides have immune function.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To study influence of Blackcurrant Polysaccharides on the immune function in mice of hypoimmunity.Methods:Immune suppression was induced by cyclophosphamide in mice.Then the mice were treated with oral Blackcurrant Polysaccharides at 0.4,0.8,1.6 g/kg daily for 10 days.The phagocytosis ability of macrophage,IL-2 and the HC50 were observed.Results:There were statistical differences in the thymus index,the spleen index,IL-2 and the HC50 among the high,middle and low dose groups.And there was statistical difference in the phagocytosis ability of macrophage in the high and middle dose groups.The content of hemolytic OD was statistically different between the high dose group and the control group.Conclusion:Blackcurrant Polysaccharides have immune function.

Key concepts: Immune system, Polysaccharide, Phagocytosis, Spleen, Medicine, Cyclophosphamide, Macrophage, Immunology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The influence of Blackcurrant Polysaccharides on the immune function in mice of hypoimmunity — Research Paper | ScholarLens