A Clinical Effective Analysis of Venlafaxine in Treatment of Somatoform Disorders

Objective To observe the clinical efficacy and side effects of venlafaxine in the treatment of somatoform disorders.Methods 68 patients with somatoform disorders were randomly assigned to receive venlafaxine or amitriptyline for six weeks,the patients were measured with clinical global impression scale (CGI-SI) and somatization in symptom checklist 90 (SCL-90) before treatment and at the 1st,2nd,4th,6th weekend after treatment,the treatment emergent symptoms scale(TESS) was used to assess the side effects at the 1st,2nd,6th weekend after treatment.Results There was no effective difference in the two groups( P 0.05),but there was difference in the effective time of drugs of the two groups( P 0.01).The score of SCL-90 somatoform gene was similar between the two groups before and after the treatment except at the end of 1-week treatment,there was no obvious significance( P 0.01).Conclusion Venlafaxine is an effective and safe drug to treat the patients with somatoform disorders.