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2004•Journal of Clinical Internal MedicineRequires access

Investigation of gastric electric activity changes in gastroesophageal reflux disease

Qin Liu

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Abstract

Objective To investigate the gastric electrical activity changes in gastroesophageal reflux disease(GERD).Methods An electrogastrography(EGG) was performed for 30 min.before and after each meal test in 43 patients with GERD diagnosed by low esophageal 24h pH+bile monitoring and in 39 healthy controls.Results The prevalence of proprandial gastric dysrhythmia in GERD was higher than that in control(58.1% vs 17.0%) and the value of preprandial instability coefficient of the dominant frequency higher that that in control.The prevalence of postprandial gastric dysrhythmia in GERD was higher than that in control(33.0% vs 15.0%).Conclusions There were abnormal preprandial and postprandial gastric electrical activities in patients with GERD.Transcutaneous EGG can be used to investigate gastric motility function in GERD.

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What this paper is about

Objective To investigate the gastric electrical activity changes in gastroesophageal reflux disease(GERD).Methods An electrogastrography(EGG) was performed for 30 min.before and after each meal test in 43 patients with GERD diagnosed by low esophageal 24h pH+bile monitoring and in 39 healthy controls.Results The prevalence of proprandial gastric dysrhythmia in GERD was higher than that in control(58.1% vs 17.0%) and the value of preprandial instability coefficient of the dominant frequency higher that that in control.The prevalence of postprandial gastric dysrhythmia in GERD was higher than that in control(33.0% vs 15.0%).Conclusions There were abnormal preprandial and postprandial gastric electrical activities in patients with GERD.Transcutaneous EGG can be used to investigate gastric motility function in GERD.

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Available abstract

Objective To investigate the gastric electrical activity changes in gastroesophageal reflux disease(GERD).Methods An electrogastrography(EGG) was performed for 30 min.before and after each meal test in 43 patients with GERD diagnosed by low esophageal 24h pH+bile monitoring and in 39 healthy controls.Results The prevalence of proprandial gastric dysrhythmia in GERD was higher than that in control(58.1% vs 17.0%) and the value of preprandial instability coefficient of the dominant frequency higher that that in control.The prevalence of postprandial gastric dysrhythmia in GERD was higher than that in control(33.0% vs 15.0%).Conclusions There were abnormal preprandial and postprandial gastric electrical activities in patients with GERD.Transcutaneous EGG can be used to investigate gastric motility function in GERD.

Key concepts: GERD, Postprandial, Medicine, Reflux, Internal medicine, Gastroenterology, Meal, Disease

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