Clinical effects of hypertonic saline and mannitol in treatment of early cerebral edema followed by cerebral hemorrhage

Objective: To investigate clinical effects of hypertonic saline joint mannitol in treatment of early cerebral edema followed by cerebral hemorrhage. Methods: One hundred and sixty cases of cerebral hemorrhage combined with early cerebral edema were randomly divided into the treatment group and the control group. All cases were treated by appropriate symptomatic treatment,then the control group was given mannitol therapy,the treatment group was treated with hypertonic saline and mannitol. The size of cerebral edema volume,hematoma and NIHSS scores in the two groups of patients before and after treatment were calculated. Results: After treatment,the size of cerebral edema volume and hematoma in both groups were significantly decreased( P 0. 05),and the treatment group improved more significantly( P 0. 05); NISHH score was significantly better( P 0. 05),and more improvement in the treatment group( P 0. 05). The efficiency in treatment group was 65. 0%,while in the control group was 41. 3%. The results of the evaluation of the treatment group were significantly better( P 0. 05). Conclusion: Hypertonic saline and mannitol can possibly promote the absorption of cerebral edema,and improve the patients' neurological function.