Comparison of Clinical Related Factors between Cases with HBeAg-negative and HBeAg-positive Liver Cirrhosis

Objective To investigate and compare the clinical characteristics of HBeAg-negative and HBeAg-positive liver cirrhosis.Methods A total of 424 hospitalized cases with HBeAg-negative and HBeAg-positive liver cirrhosis were analyzed retrospectively.The factors included age,gender,constitutes of liver cirrhosis,HBVDNA level,complications and Child-pugh graduation.Results HBeAg-negative liver cirrhosis patients group totally 252 cases,215 male and 37 female,the gender ratio was roughly 5.81:1.HBeAg-positive chronic liver Diseases patients group totally 172 cases,149 male and 23 female,the gender ratio was roughly 6.48∶1.The serum HBVDNA levels in HBeAg-negative patients group was lower than that in HBeAg-positive patients group(P0.01).No significant difference was found in upper gastrointestinal hemorrhage,hepatic encephalopathy,infection of abdominal cavity,electrolyte disturbances and hepatorenal syndrome between two groups(P0.05).Conclusion HBeAgnegative patients had older age and lower HBV DNA level than HBeAg-positive patients had.