A Clinical Trial of Neonatal Respiratory Distress Syndrome Treated With Pulmonary And Mechanical Ventilation

Objective:To expore effects of pulmonary surfactant (PS) combined with mechanical ventilation on neonatal respiratory distress syndrome (NRDS). Methods: Twenty-five newborns with NRDS were treated with PS and mechanical ventilation, their clinical symptoms, blood-gas analysis, X-ray chest films, the parameters related to mechanical ventilation were observed and analyzed before and after treatment. Results: After treatment with PS and mechanical ventilation, these newborns got obviously improvement in clinical symptoms and X-ray chest films in which the lucency was increased and grains-ramified shades disappeared. The values of blood-gas analysis and the parameters related to mechanical ventilation such as fraction of inspired oxygen (FiO2), peak inspiratory pressure (PIP), and positive end expiratory pressure (PEEP) were decreased. Conclusion: PS combined with mechanical ventilation is an effective and rapid way to treat NRDS.