Adenosine stress myocardial perfusion imaging and dual-source computed tomography for detecting coronary heart disease

Objective To explore the value of adenosine(ADE) stress gated myocardial perfusion imaging(G-MPI) and dual-source CT coronary angiography(DSCTCA) in diagnosis of coronary artery disease(CAD).Methods Fifty-three patients with low,medium and high probability of CAD underwent resting(REST),ADE stress G-MPI and DSCTCA,then they underwent CAG within 4 weeks.MPI results were analyzed using the American Heart Association 17 segment 5-point scale(0—4 points) visual semi-quantitative method,and the resting and stress rating of the difference 1 were identified as reversible defect.Coronary stenosis were determined using international common law of DSCTCA visual diameter and were divided into normal and stenosis 50% or ≥50%.Taking CAG results as gold standards and stenosis ≥50% defined as CAD,diagnostic value of MPI and DSCTCA was compared.Results According to CAG results,the sensitivity,specificity and accuracy of G-MPI and DSCTCA in diagnosis of CAD was 94.44%(34/36),52.94%(9/17),81.13%(43/53) and 88.89%(32/36),88.24%(15/17),88.68%(47/53),respectively(χ2=9.28,P=0.005).Conclusion G-MPI and DSCTCA both have high value in diagnosis of CAD,combination of these two methods can improve the diagnostic utility of CAD through obtaining both functional and anatomical information.