The effect of clinical study in agencied COPD insulting severe respiratory failure by using sequential invasive and non-invasive mechanical ventilation

Objective To observe the clinical therapeutic effect of sequential invasive and non-invasive mechanical ventilation in agencied COPD insulting severe respiratory failure and to explore the superiority of sequential mechanical ventilation. Methods 21 patients with agencied COPD insulting severe respiratory failure were randomly selected, who underwent sequential invasive and non-invasive mechanical ventilation. 19 patients underwent conventional invasive mechanical ventilation treatment. The measured were recorded and analyzed and compared of the basics of patients before treatment and the invasive mechanical ventilation time, the stayed RICU time, total mechanical ventilation time, total length of stay in hospital time; the incidence of ventilator associated pneumonia (VAP), and incidence of repeated tracheal intubation. Results Sequential invasive and non-invasive mechanical ventilation in agencied COPD insulting severe respiratory failure has significant therapeutic effect on shortening the invasive mechanical ventilation time, the stayed RICU time and total length of stay in hospital time (P0.05). The incidence of ventilator associated pneumonia (VAP), and incidence of repeated tracheal intubation in sequential invasive and non-invasive mechanical ventilation was lower than that using conventional treatment (P0.05). Conclusion After infection of the bronchia and lung were controlled, and the character of phlegm had improved, sequential invasive and non-invasive mechanical ventilation had superiority.