2011Neural Injury and Functional ReconstructionRequires access

Risk Factors for Early Hematoma Enlargement in Hypertensive Intracerebral Hemorrhage

Xiuju Wang

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Abstract

Objective: To explore the risk factors for early hematoma enlargement in hypertensive intracerebral hemorrhage(HICH).Methods: The clinical data of 285 patients with HICH have been reviewed.All the patients were divided into growing hematoma group and stable hematoma group according to the existence of early hematoma enlargement and comparatively studied.Results: Seventy-seven cases(27.02%) showed hematoma enlargement.The occurrence of hematoma enlargement in patients with HICH within 6 hours after onset was significantly frequent(P=0.000).Multivariate analysis demonstrated that the course of hypertension,the blood pressure initially measured at admission,early administration of mannitol,the dosage of mannitol in 24 h,Glasgow Coma Scale(GCS),alcoholism,the site and shape of hematoma were associated with hematoma enlargement.Conclusion: Multiple risk factors and mechanisms are involved in hematoma growth in HICH.

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What this paper is about

Objective: To explore the risk factors for early hematoma enlargement in hypertensive intracerebral hemorrhage(HICH).Methods: The clinical data of 285 patients with HICH have been reviewed.All the patients were divided into growing hematoma group and stable hematoma group according to the existence of early hematoma enlargement and comparatively studied.Results: Seventy-seven cases(27.02%) showed hematoma enlargement.The occurrence of hematoma enlargement in patients with HICH within 6 hours after onset was significantly frequent(P=0.000).Multivariate analysis demonstrated that the course of hypertension,the blood pressure initially measured at admission,early administration of mannitol,the dosage of mannitol in 24 h,Glasgow Coma Scale(GCS),alcoholism,the site and shape of hematoma were associated with hematoma enlargement.Conclusion: Multiple risk factors and mechanisms are involved in hematoma growth in HICH.

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Available abstract

Objective: To explore the risk factors for early hematoma enlargement in hypertensive intracerebral hemorrhage(HICH).Methods: The clinical data of 285 patients with HICH have been reviewed.All the patients were divided into growing hematoma group and stable hematoma group according to the existence of early hematoma enlargement and comparatively studied.Results: Seventy-seven cases(27.02%) showed hematoma enlargement.The occurrence of hematoma enlargement in patients with HICH within 6 hours after onset was significantly frequent(P=0.000).Multivariate analysis demonstrated that the course of hypertension,the blood pressure initially measured at admission,early administration of mannitol,the dosage of mannitol in 24 h,Glasgow Coma Scale(GCS),alcoholism,the site and shape of hematoma were associated with hematoma enlargement.Conclusion: Multiple risk factors and mechanisms are involved in hematoma growth in HICH.

Key concepts: Hematoma, Medicine, Glasgow Coma Scale, Intracerebral hemorrhage, Intracerebral hematoma, Mannitol, Spontaneous intracerebral hemorrhage, Blood pressure

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