2011•Liaoning zhongyi zazhiRequires access

Influence of Liang Xue Tong Yu Fang on proliferation 、apoptosis and related gene expression in VEC Injured by H_2O_2

Muhan Li

Abstract

Objective:To observe the effect of the prescription on proliferation,apoptosis and P21 、P53 gene expression in VEC injured by H2O2.Methods:The method of MTT and flow cytometry(FCM) were adopted to determine cellular proliferation and apoptosis in each group.Expression of P21 and P53 gene was measured by the method of FQ-PCR.Results:Liang Xue Tong Yu Fang can promote VEC cellular proliferation,inhibit its apoptosis and reduce P21 and P53 gene expression;It can antagonism damage of VEC by H2O2.This could be the mechanism of Liang Xue Tong Yu Fang against hemorrhagic stroke.Conclusion:

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Apoptosis, Medicine, Flow cytometry, Gene, Traditional medicine, Cell growth, Gene expression, Cancer research