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Optimization of Extraction Process for Ephedrine from HERBA EPHEDRAE

WU Jia-quan

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Abstract

[Objective] To optimize the extraction parameters of ephedrine,so as to provide basis for improving the extracting method for ephedrine.[Method] Effects of pH value,shaking duration,phase ratio and extraction steps on the extraction percentage of ephedrine were investigated using ethyl acetate as extraction solvent.[Result] The optimum extraction conditions were:pH value ranging from 12 to 13,shaking duration of 2.0min,1:1 of phase ratio and extraction steps of 3.[Conclusion] Little in pollution and simple in process,the ethyl acetate extraction can be employed as a method for extracting ephedrine from HERBA EPHEDRAE.

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[Objective] To optimize the extraction parameters of ephedrine,so as to provide basis for improving the extracting method for ephedrine.[Method] Effects of pH value,shaking duration,phase ratio and extraction steps on the extraction percentage of ephedrine were investigated using ethyl acetate as extraction solvent.[Result] The optimum extraction conditions were:pH value ranging from 12 to 13,shaking duration of 2.0min,1:1 of phase ratio and extraction steps of 3.[Conclusion] Little in pollution and simple in process,the ethyl acetate extraction can be employed as a method for extracting ephedrine from HERBA EPHEDRAE.

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Available abstract

[Objective] To optimize the extraction parameters of ephedrine,so as to provide basis for improving the extracting method for ephedrine.[Method] Effects of pH value,shaking duration,phase ratio and extraction steps on the extraction percentage of ephedrine were investigated using ethyl acetate as extraction solvent.[Result] The optimum extraction conditions were:pH value ranging from 12 to 13,shaking duration of 2.0min,1:1 of phase ratio and extraction steps of 3.[Conclusion] Little in pollution and simple in process,the ethyl acetate extraction can be employed as a method for extracting ephedrine from HERBA EPHEDRAE.

Key concepts: Ephedrine, Extraction (chemistry), Chromatography, Ethyl acetate, Chemistry, Solvent, Anesthesia, Medicine

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