2007Lingnan Journal of Emergency MedicineRequires access

Effect of Esmolol on the Stress Response to Intubation

Long-hui Cao, Zhou Jian-hua, Weian Zeng, Wenqian Lin

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Abstract

Objective: To explore the effect of esmolol on the stress response to intubation. Methods: Sixty patients scheduled for elective non-cardiac surgery were randomly divided into two groups (Group E and C), 30 for each. In each group, MAP, HR and CO were recorded at preinduction, before the administration of esmolol or saline (baseline), preintubation, intubation and 1min, 3min, 5min after intubation. Results: After intubation, MAP, HR and CO all increased in two groups, but the average maximum of group C increase is significantly higher than group E (P 0.05). Conclusion: Esmolol can suppress the stress response to intubation.

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What this paper is about

Objective: To explore the effect of esmolol on the stress response to intubation. Methods: Sixty patients scheduled for elective non-cardiac surgery were randomly divided into two groups (Group E and C), 30 for each. In each group, MAP, HR and CO were recorded at preinduction, before the administration of esmolol or saline (baseline), preintubation, intubation and 1min, 3min, 5min after intubation. Results: After intubation, MAP, HR and CO all increased in two groups, but the average maximum of group C increase is significantly higher than group E (P 0.05). Conclusion: Esmolol can suppress the stress response to intubation.

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Available abstract

Objective: To explore the effect of esmolol on the stress response to intubation. Methods: Sixty patients scheduled for elective non-cardiac surgery were randomly divided into two groups (Group E and C), 30 for each. In each group, MAP, HR and CO were recorded at preinduction, before the administration of esmolol or saline (baseline), preintubation, intubation and 1min, 3min, 5min after intubation. Results: After intubation, MAP, HR and CO all increased in two groups, but the average maximum of group C increase is significantly higher than group E (P 0.05). Conclusion: Esmolol can suppress the stress response to intubation.

Key concepts: Esmolol, Medicine, Intubation, Anesthesia, Saline, Fight-or-flight response, Elective surgery, Heart rate

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