2002•Letters in BiotechnologyRequires access

Telomeres,telomerase and cellular senescence

Qing Jia

Abstract

Telomeres and telomerase are in the spotlight of modern biological study.There are causal relationship be-tween telomere loss and replicative senescence,and telomerase activation and cellular senescence and immortaliza-tion.The formation and function of telomeres and telomerase and the close relationship between aging and them are reviewed,on which telomerase's application in aging control and cancer treatment is introduced.

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Available abstract

Key concepts: Telomerase, Telomere, Senescence, Cellular senescence, Telomerase RNA component, Biology, Cell biology, Function (biology)