Telomeres and Telomerase in Aging and Cancer
Michel M. Ouellette
Abstract
Michel M. Ouellette
Abstract
Abstract Telomeres protect the ends of chromosomes and shorten each time somatic human cells divide. As a consequence, cells enter senescence after a limited number of divisions. The enzyme telomerase expressed in rare cells of the skin, blood and intestine can prevent the shortening of telomeres and extend cellular lifespan.
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Abstract Telomeres protect the ends of chromosomes and shorten each time somatic human cells divide. As a consequence, cells enter senescence after a limited number of divisions. The enzyme telomerase expressed in rare cells of the skin, blood and intestine can prevent the shortening of telomeres and extend cellular lifespan.
Key concepts: Telomere, Telomerase, Somatic cell, Senescence, Biology, Cellular senescence, Cellular Aging, Cancer