The clinical study on the safety and effectiveness of aspirin and clopidogrel treatment of acute cerebral infarction in type 2 diabetes

Objective to explore the effectiveness and safety of the treatment of acute cerebral infarction in type 2 diabetes by combing aspirin and clopidogrel treatment.Methods select 102 cases admitted within 24 hours onset of acute cerebral infarction in type 2 diabetes,who were randomly divided into two groups,one was aspirin and clopidogrel group andn other was aspirin group.NiNSS rating criteria was used to evaluate ischemic stroke in accordance with valid and invalid.To observe clinical results,side effects and so on on the 7th and 30th day.Also the changes of serum CRP was compared between the two groups.Results the efficiency after 7days treatment,the aspirin and clopidogrel group was 90.0%,while the control group was 73.1%(P0.05).after 30 days,the efficiency of aspirin and clopidogrel group was superior than aspirin group(P0.05).none of the serious side effects was shown in this manuscript.Also,changes of serum CRP levels was difference between the two groups(P0.05).Conclusion compared with aspirin as a single load,it was efficient that aspirin and clopidogrel of loading dose treating acute cerebral infarction in type two diabetes patients.Chich can prevent the progress of stroke,improve the prognosis.