Document analysis and precautions on anaphylactic shock induced by Compound Glycyrrhizin Injection

Objective To explore the clinical characteristics and rules of anaphylactic shock induced by Compound Glycyrrhizin Injection, and to provide the references for the rational use of drugs in clinic. Methods China Journal Full-text Database(CNKI), Chinese Science and Technology Journal Full-text Database(VIP), Wangfang Database, etc were retrieved, and the literature involving cases were analyzed and discussed. Results There were 17 anaphylactic shock cases caused by Compound Glycyrrhizin Injection, and they had no obvious relationship with age and gender. Fifteen cases(88.2%) occured in the medication within 20 min after iv infusion. There was no significant difference in clinical manifestations and rescue compared with other anaphylactic shock. After active anti-anaphylactic shock rescue, all patients returned to normal with no deaths. It was the security risk to anaphylactic shock that medical staff didn't pay attention to ADR at the initial treatment stage. Conclusion Anaphylactic shock induced by Compound Glycyrrhizin Injection is not rare, and clinical medical workers should pay attention to it.