Clinical research on treatment of hypertensive cerebral hemorrhage with hyperbaric oxygen

Objective To observe the effect of hyperbaric oxygen (HBO) therapy early after the hemorrhage on neurological function rehabilitation and prognosis in patients with hypertensive cerebral hemorrhage. Methods Eighty-seven patients with hypertensive cerebral hemorrhage were randomly divided into two groups, i.e. routine treatment (control) group (n=45) and HBO therapy group (n=42), in which HBO therapy was performed once per day 5 days after the cerebral hemorrhage and lasted 25 days. The curative effects were compared between both the HBO therapy and control groups 25 days and 6 months after HBO therapy. Results The scores of GCS were significantly higher 1 month after the treatment than those before the treatment in both the groups (P0.05 or P0.01). The scores of GCS was significantly higher in the HBO therapy group than those in the control group 1 month after the treatment (P0.05). The neurological deficit score was significantly lower, the area of cerebral edema was significantly smaller, and the cognitive function was significantly better in HBO therapy group than those in the control group 1 month after treatment (P0.05). The rate of good prognosis (76.19%,32/42) was significantly higher in HBO therapy group than that (46.67%,21/45) in the control group 6 months after the treatment (P0.05). Conclusion The rehabilitation of the neurological function and cognitive function may be promoted and prognosis may be improved by HBO therapy in the patients with hypertensive cerebral hemorrhage.