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2005•Chinese Journal of Otorhinolaryngology-skull Base SurgeryRequires access

Study on efficacy and safety of desloratadine in the treatment of allergic rhinitis

Weihong Jiang

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Abstract

Objective To preliminarily evaluate the safety and efficacy of the domestic desloratadine tablet and recommend its clinic doses. Methods A randomized, single-blind, multicenter, loratadine-controlled trial was performed. Results A total of 225 patients were involved in the trial. Desloratadine can obviously alleviate patients' clinic symptoms, with its effect similar to that of loratadine tablet. No serious adverse effects were found. The incidence rate of side effects was about 12.2%. Side effects mainly include dry mouth followed by drowsiness and dizziness. Safe indexes between desloratadine and loratadine were not significantly different. Conclusion The efficacy and incidence of desloratadine and loratadine are similar in treatment of allergic rhinitis. Domestic desloratadine tablet is effective and safe for allergic rhinitis.

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What this paper is about

Objective To preliminarily evaluate the safety and efficacy of the domestic desloratadine tablet and recommend its clinic doses. Methods A randomized, single-blind, multicenter, loratadine-controlled trial was performed. Results A total of 225 patients were involved in the trial. Desloratadine can obviously alleviate patients' clinic symptoms, with its effect similar to that of loratadine tablet. No serious adverse effects were found. The incidence rate of side effects was about 12.2%. Side effects mainly include dry mouth followed by drowsiness and dizziness. Safe indexes between desloratadine and loratadine were not significantly different. Conclusion The efficacy and incidence of desloratadine and loratadine are similar in treatment of allergic rhinitis. Domestic desloratadine tablet is effective and safe for allergic rhinitis.

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Available abstract

Objective To preliminarily evaluate the safety and efficacy of the domestic desloratadine tablet and recommend its clinic doses. Methods A randomized, single-blind, multicenter, loratadine-controlled trial was performed. Results A total of 225 patients were involved in the trial. Desloratadine can obviously alleviate patients' clinic symptoms, with its effect similar to that of loratadine tablet. No serious adverse effects were found. The incidence rate of side effects was about 12.2%. Side effects mainly include dry mouth followed by drowsiness and dizziness. Safe indexes between desloratadine and loratadine were not significantly different. Conclusion The efficacy and incidence of desloratadine and loratadine are similar in treatment of allergic rhinitis. Domestic desloratadine tablet is effective and safe for allergic rhinitis.

Key concepts: Desloratadine, Loratadine, Medicine, Incidence (geometry), Adverse effect, Randomized controlled trial, Anesthesia, Side effect (computer science)

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Study on efficacy and safety of desloratadine in the treatment of allergic rhinitis — Research Paper | ScholarLens