Effect of Intra-arterial Thrombolysis Combined with Mechanical Thrombectomy in Treatment of Patients with Acute Cerebral Infarction

Objective To observe the clinical effect of super selective intra-arterial thrombolysis combined with mechanical thrombectomy in treatment of acute cerebral infarction. Methods A total of 28 patients with acute cerebral infarction during January 2006 and January 2014 underwent super selective intra-arterial thrombolysis combined with mechanical thrombectomy treatment,and the conventional treatments such as expansion and antiplatelet treatments were given at the same time. The immediately postsurgical revascularization rate,and the scores of the National Institutes of Health stroke scale( NIHSS) and activity of daily living( ADL) on 1 h,2 weeks and 3 months after the treatment were evaluated. Results After the treatment,the complete recanalization rate was 75%,and partial recanalization was 25%,the residual stenosis was more than 80% in 4 patients after recanalization,and stenting insertion was performed at the same time; the scores of NIHSS and ADL on 1 h,2 weeks and 3 months after the operation in the 27 patients were improved( P 0. 05),except 1 patient who died of central respiratory failure. Conclusion The intra-arterial thrombolysis combined with mechanical thrombectomy in treatment of acute cerebral infarction is safe and effective.