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ANALYSIS OF CURATIVE EFFECTS OF INTRA-ARTERY SELECTIVE THROMBOLYTIC THERAPY FOR 36 PATIENTS OF ACUTE ISCHEMIC CEREBRAL INFARCTION

Junde Qin

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Abstract

[Objective]To explore curative effects of intra-artery selective thrombolytic therapy for 36 patients of acute ischemic cerebral infarction.[Methods]36 patients of super early stage cerebral infarction were selected as research group,using intra-artery selective thrombolytic therapy,intubation urokinase 1 million U/min continuous pump,dosage 25 to 100 million units;And other 36 patients with the same age,illness,the incidence of time matching super early of acute cerebral infarction were as control group,given intravenous thrombolysis treatment,the urokinase 1.5 million U join saline 100ml canister,intravenous drip 30min.Recorded patients of two groups before and after fibrinolytic therapy for nerve change and their prognosis.[Results](1)NIHSS scores of patients in two groups before treatment had no significant difference(P﹥0.05).After treatment,NIHSS scores in research group were significantly lower than control group(P﹤0.05).(2)20 cases in the research group with significant effect(55.6%),the total effective rate was 77.8%(28/36);11 cases in the control group with significant effect(30.6%),with the total effective rate of 69.4%(25/36)(P﹤0.05).[Conclusion]The intra-artery selective thrombolytic therapy for patients of acute ischemic cerebral infarction could recover patients' brain blood perfusion,block the pathological process of cerebral infarction,which has more significant curative effect.

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[Objective]To explore curative effects of intra-artery selective thrombolytic therapy for 36 patients of acute ischemic cerebral infarction.[Methods]36 patients of super early stage cerebral infarction were selected as research group,using intra-artery selective thrombolytic therapy,intubation urokinase 1 million U/min continuous pump,dosage 25 to 100 million units;And other 36 patients with the same age,illness,the incidence of time matching super early of acute cerebral infarction were as control group,given intravenous thrombolysis treatment,the urokinase 1.5 million U join saline 100ml canister,intravenous drip 30min.Recorded patients of two groups before and after fibrinolytic therapy for nerve change and their prognosis.[Results](1)NIHSS scores of patients in two groups before treatment had no significant difference(P﹥0.05).After treatment,NIHSS scores in research group were significantly lower than control group(P﹤0.05).(2)20 cases in the research group with significant effect(55.6%),the total effective rate was 77.8%(28/36);11 cases in the control group with significant effect(30.6%),with the total effective rate of 69.4%(25/36)(P﹤0.05).[Conclusion]The intra-artery selective thrombolytic therapy for patients of acute ischemic cerebral infarction could recover patients' brain blood perfusion,block the pathological process of cerebral infarction,which has more significant curative effect.

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Available abstract

[Objective]To explore curative effects of intra-artery selective thrombolytic therapy for 36 patients of acute ischemic cerebral infarction.[Methods]36 patients of super early stage cerebral infarction were selected as research group,using intra-artery selective thrombolytic therapy,intubation urokinase 1 million U/min continuous pump,dosage 25 to 100 million units;And other 36 patients with the same age,illness,the incidence of time matching super early of acute cerebral infarction were as control group,given intravenous thrombolysis treatment,the urokinase 1.5 million U join saline 100ml canister,intravenous drip 30min.Recorded patients of two groups before and after fibrinolytic therapy for nerve change and their prognosis.[Results](1)NIHSS scores of patients in two groups before treatment had no significant difference(P﹥0.05).After treatment,NIHSS scores in research group were significantly lower than control group(P﹤0.05).(2)20 cases in the research group with significant effect(55.6%),the total effective rate was 77.8%(28/36);11 cases in the control group with significant effect(30.6%),with the total effective rate of 69.4%(25/36)(P﹤0.05).[Conclusion]The intra-artery selective thrombolytic therapy for patients of acute ischemic cerebral infarction could recover patients' brain blood perfusion,block the pathological process of cerebral infarction,which has more significant curative effect.

Key concepts: Medicine, Urokinase, Thrombolysis, Cerebral infarction, Infarction, Artery, Anesthesia, Cardiology

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ANALYSIS OF CURATIVE EFFECTS OF INTRA-ARTERY SELECTIVE THROMBOLYTIC THERAPY FOR 36 PATIENTS OF ACUTE ISCHEMIC CEREBRAL INFARCTION — Research Paper | ScholarLens