ScholarLens Back to search
2011•Zhongguo yiyuan ganranxue zazhiRequires access

Clinical significance of determination of CSF IL-6 and β_2-MG for infection of central nervous system in paediatric patients

LI Feng-er

Open publisher page 0 citations

Abstract

OBJECTIVE To study the function and Clinical significance of CSF IL-6 and β2-MG in infection of the central nervous system in pediartic patients.METHODS IL-6 was determined by ELISA,β2-MG was determined by LAT.RESULTS The contents of IL-6 and β2-MG in CSF of purulent meningitis were(278.5±63.7) ng/L and(9.4±2.6) mg/L;Their contents in viral meningitis were(101.2±30.5) ng/L and(5.1±1.7) mg/L;Their contents in control group were(47.0±6.1) ng/L and(1.8±0.5) mg/L.The levels of IL-6 and β2-MG in acute stage were significantly higher than those of the cases in convalescent stage and control group(P0.01).CONCLUSION It has great clinical significance to detect the levels of IL-6 and β2-MG for the differentiating diagnosis of paediatric patients with the central nervous system infection.

About this research paper

What this paper is about

OBJECTIVE To study the function and Clinical significance of CSF IL-6 and β2-MG in infection of the central nervous system in pediartic patients.METHODS IL-6 was determined by ELISA,β2-MG was determined by LAT.RESULTS The contents of IL-6 and β2-MG in CSF of purulent meningitis were(278.5±63.7) ng/L and(9.4±2.6) mg/L;Their contents in viral meningitis were(101.2±30.5) ng/L and(5.1±1.7) mg/L;Their contents in control group were(47.0±6.1) ng/L and(1.8±0.5) mg/L.The levels of IL-6 and β2-MG in acute stage were significantly higher than those of the cases in convalescent stage and control group(P0.01).CONCLUSION It has great clinical significance to detect the levels of IL-6 and β2-MG for the differentiating diagnosis of paediatric patients with the central nervous system infection.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE To study the function and Clinical significance of CSF IL-6 and β2-MG in infection of the central nervous system in pediartic patients.METHODS IL-6 was determined by ELISA,β2-MG was determined by LAT.RESULTS The contents of IL-6 and β2-MG in CSF of purulent meningitis were(278.5±63.7) ng/L and(9.4±2.6) mg/L;Their contents in viral meningitis were(101.2±30.5) ng/L and(5.1±1.7) mg/L;Their contents in control group were(47.0±6.1) ng/L and(1.8±0.5) mg/L.The levels of IL-6 and β2-MG in acute stage were significantly higher than those of the cases in convalescent stage and control group(P0.01).CONCLUSION It has great clinical significance to detect the levels of IL-6 and β2-MG for the differentiating diagnosis of paediatric patients with the central nervous system infection.

Key concepts: Clinical significance, Central nervous system, Viral meningitis, Medicine, Meningitis, Gastroenterology, Internal medicine, Cerebrospinal fluid

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Clinical significance of determination of CSF IL-6 and β_2-MG for infection of central nervous system in paediatric patients — Research Paper | ScholarLens