A clinical study on different anesthesia medication in combined and epidural anesthesia in caesarean section

Objective: To investigate the safety and effect of ropivacaine,bupivacaine and teracaine in caesarean section in combined spinal and epidural anesthesia.Methods: Ninety parturients were randomly divided into three groups.Made high density mixture from 0.89% ropivacaine(group A),0.75% bupivacaine(group B) and 1% teracaine(group C) 1 ml,respectively puls,10% glucose 1 ml and 3% ephedrine 1 ml respectively.In all parturients,a Tuohy needle(B.D) was introduced into the L2-3 epidural space,and 2~3 ml medicine was injected into subarachnoid space in 0.1 ml/s.Parturients received extradural injection 0.89% ropivacaine or 2% lidocaine 5~10 ml to maintain block level.To compare difference in sensory block,motor block and recovery time in three groups.Side-effects and effect on neonate score were observed.Results: The onset time of maximum sensory block and motor block in group A was prolonged compared with group B and group C(P0.05);There were no significantly difference in maximum sensory block level in three groups(P0.05);Effect time in group A was shorter than group B and group C(P0.05); Onset time of motor block in group A was prolonged compared with group B and group C(P0.05),maximum Bromage score was 0~1 in group A,significantly smaller(P0.05),time of maximum motor block was prolonged(P0.05),time of motor motor block disappear was shorter(P0.05);The incidence of hypotension,nausea vomiting in group A was lower(P0.05);Neonatal Apgar score and incidence of postoperation headache had no significantly difference(P0.05).Conclusion: Ropivacaine is safety and high effective in caesarean section in combined spinal and epidural anesthesia for parturient and neonatal.