Changes of anorectal motility and rectal sensation in patients with ulcerative colonitis during active and no-active period

Objective To study the changes of anorectal motility and rectal sensation in the patients with ulcerative colonitis (UC ) during active and no-active period. Methods Anorectal motility and rectal sensation were investigated by multispot balloon probe in 30 patients with active UC,22 patients with no active UC and 30 healthy subjects (HS) were as controlled group. Results (1)When abdominal pressure was increased,the net increased pressure of anal sphincter was (2.9±1.0) kPa in active UC,(3.1±0.8) kPa in no active UC. They were lower than that in HS [(3.90±1.58) kPa](P0.05). (2)The rectal lowest volume of sensory threshold,the maximal volume of tolerance and maximal compliance were (68.3±39.4) ml,(170.6±59.8) ml, (23.3±12.6) ml/kPa in active UC,(74.2±40.3) ml,(190.0±49.3) ml,(28.1± 10.1) ml/kPa in no active UC.They were lower than those in HS [(84.5±45.0) ml,(210.3±46.4) ml,(30.9±13.2) ml/kPa],[WTBX]P0.01 or P0.05.(3)The rectal lowest volume of sensory threshold,the maximal volume of tolerance and maximal compliance in no active UC were higher than those in active UC (P0.01 and P0.05). Conclusions (1)There are some anorectal motility disturbances in UC.(2) Higher sensitivity,lower tolerance,lower compliance of rectum and weakened anal automatic control function in UC may be associated with diarrhea and frequent defecation.(3)The anorectal motility and rectal sensation are improved in NAUC.