2011•Chinese Journal of Gastroenterology and HepatologyRequires access
Analysis of risk factors about portal hypertensive gastropathy after esophageal varices ligation
Weiqiang Zhang
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Abstract
Objective To analyze the various risk factors with aggravate portal hypertensive gastropathyc(PHG) after esophageal variceal ligation(EVL).Methods A retrospective analysis of 154 cases with liver cirrhosis underwent the increased degree of PHG after EVL.Results Forty-three patients after portal azygous devascularization with H.pylori-positive,severe PHG total composition ratio were 51.16% and 74.42% before and after EVL(P0.05);by liver function Child-Pugh grade(A + B) and C groups,proportion ratios of each group patients with severe PHG were 30.77%,38.46%(P 0.05) and 60.00%,90.00% before and after EVL(P0.05).Thirty-three patients with portal azygous devascularization history of H.pylori negative,the total composition ratios of severe PHG were 21.21% and 36.36% before and after EVL(P0.05).According to liver function by Child-Pugh(A+B) grade,C grade group,total composition ratios of earch group patients with severe PHG were 14.29%,21.43%(P0.05) and 26.32%,47.37% before and after EVL(P0.05).Fifteen H.pylori postive patients without history of portal azygous devascularization,the total composition ratios of severe PHG were 20.00% and 40.00% before and after EVL(P0.05);by liver function Child-Pugh(A+B) grade,C grade group,proportion ratios of each group patients with severe PHG were 16.67%,16.67%(P0.01) and 22.22%,55.56%(P0.01) before and after EVL.Forty-six patients without portal azygous devascularization history of H.pylori negative,overall proportion ratios were 17.39% and 23.91%(P 0.05) before and after EVL;by liver function Child-Pugh(A+B) and C-level group,the proportion ratios of each group patients with severe PHG were 14.29%,19.05%(P0.05) and 20.00%,28.00% before and after EVL(P0.05).Conclusion Composition ratio of cirrhotic patients with severe PHG after EVL and liver function in Child-Pugh classification is significantly correlated;portal azygous devascularization,H.pylori infection in patients with cirrhosis are all the important dangerous factors of severe PHG after EVL.