Investigation on Plague F1-antibody in Sera of Population in Plague Natural Foci of Apodemus chevrieri and Eothenomys miletus in Yunnan Province

ObjectiveTo realize the level and distribution of plague F1-antibody in sera of population in plague natural foci of Apodemus chevrieri and Eothenomys miletus in Yunnan Province.Methods279 sera samples from high-risk population in plague natural foci and 235 serum samples from healthy population in low-risk area were detected by indirect hemagglutination(IHA) with the diagnosis standard of positive titer no less than 1∶20.ResultsOut of 279 serum samples from the high-risk population,34 samples were positive in plague F1-antibody with the positive rate of 12.19%.2 positive samples were caused by silent infection and the positive titer of one rehabilitated patient was 1∶640.235 serum samples of healthy people from non-plague area were all negative.ConclusionsThe positive titers detected in this survey of plague F1-antibody in sera of population from the plague natural foci result from repeated inoculation of plague vaccine.However,a few people with serum F1-positive have not inoculated the plague vaccine.So the threaten of the plague natural foci can not be ignored and the surveillance and protection of plague should be strengthened.